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Abstract: 

Immunologists expect vaccines that protect against viral illnesses to also reduce transmission of the virus after vaccination. But it’s actually tricky to figure out for sure if vaccinated people are not spreading the germ. Preliminary evidence seems to suggest the COVID-19 vaccines make it less likely someone who’s vaccinated will transmit the coronavirus, but the proof is not yet ironclad. This article weighs the current evidence for “sterilizing immunity,” and concludes that we do not yet know the “correlates of protection,” factors that predict just how protected someone is against the coronavirus.

Keywords: Sterilizing Immunity; Correlates of Protection

Affiliations:  1: Vanderbilt University Medical Center.